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On November 12, 2025, HLI PIs Drs. Pat Camp and Graeme Koelwyn and Science and Grant Writers Drs. Kasia Adolphs and Evan Phillips participated in a Providence Research Trainee Collaborative Grant Writing Workshop.

During the session, moderated by PR Research Director Dr. Scott Tebbutt, panelists shared key strategies for writing fellowship and grant applications. Topics included the use of storytelling in grant writing, how best to align an application with funder priorities, balancing authenticity and strategic positioning, common pitfalls to avoid, handling rejection and re-submission, mentoring and leadership – and more.

Key Takeaways

✅ Tailor every application to the funder’s priorities and evaluation criteria.

✅ Use storytelling strategically to connect past experiences with future goals.

✅ Plan timelines early – avoid last-minute submissions.

✅ Engage authentically with EDI principles and community relationships.

✅ Seek feedback and mentorship to strengthen your application.

This event was part of a series of events organized by the Providence Research Trainee Collaborative to support trainees in successfully navigating their career paths. Following the panel discussion, trainees were encouraged to join a networking session, which provided the opportunity to explore and discuss topics further.

A big thank you to Kaylie Friess (Project Manager) and Josephine Jung (Director, Special Projects and Strategy) from Providence Research for organizing the event!

Story by Basak Ashley Sahin. Edited by Tiffany Chang.

From personal experience to advocacy

Leading by example

Creating space for others to thrive


Outside of the lab

Job Description:

A Research Associate (RA) position is available at the University of British Columbia (UBC), Division of Respiratory Medicine, Department of Medicine under the direction of Dr. Scott J. Tebbutt, Professor of Medicine of UBC Faculty of Medicine and Principal Investigator and Director of Education of Centre for Heart Lung Innovation at St Paul’s Hospital.

The RA will work with an interdisciplinary and international team to support the Immunophenotyping of a COVID-19 pneumonia Cohort (IMPACC) Study. The RA and Dr. Tebbutt’s team members will identify molecular endotypes of long-COVID-19 (also called Post COVID-19 Syndrome) during and after COVID-19 infection, in peripheral blood, plasma, nasal swabs, and airway tissue samples, by carrying out unsupervised analysis of multi-omics profiles at a single time-point or considering the time-course profile during infection. Dr. Tebbutt’s team aims to characterize the molecular heterogeneity during COVID-19 infection and to develop biomarkers of prognostic significance as they relate to the development of long-COVID-19. The distinct molecular patterns associated with each endotype may, in turn, help elucidate novel mechanisms of action and inform drug discovery and repurposing efforts.

The RA will play a critical role in the project team, providing scientific and pulmonology-based expertise to support hypothesis generation, planning, coordination, and identification of host molecular endotypes associated with diverse COVID-19 outcomes and new variants in a longitudinal multi-omics cohort study of 1000 patients. The RA will be responsible for several domains, including, but not limited to: project coordination, critical evaluation of clinical data, applications for funding, communication with collaborators and stakeholders, The RA will provide additional support to the Principal Investigator and collaborators as needed. The COVID-19 pandemic has created a climate of rapidly evolving information, goals and questions, and the RA will be expected to respond quickly and adapt to changing demands and short timelines.

Responsibilities will include, but will not be limited to:

Requirements:

Duration and salary:

The position will begin March 1, 2026 for a period of 1 year with the possibility of extension.

Salary is $76,128.00 per annum plus benefits.

Application:

The deadline for interested individuals is December 10, 2025. Applicants should send a cover letter and curriculum vitae to Dr. Tebbutt: scott.tebbutt@hli.ubc.ca

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

By Gurpreet Singhera
Gurpreet Singhera is the Bruce McManus Cardiovascular Biobank Manager.
An early picture of me in 2002 (blue arrow) with my HLI family.
Processing a patient’s donated explanted heart for biobanking.
Introducing an attentive group of High School students to biomedical research.

“This support is coming at a critical phase in our research.
It’s a tremendous show of faith from the Beedie family in the importance of our work.”

— Dr. Gordon Francis

For the full story, please visit: https://helpstpauls.com/stories/2-25-million-donation-from-beedie-foundation-advances-innovative-cardiac-research-and-care/

https://healthresearchbc.ca/awardrecipient/2025-research-trainee-award-recipients/

By Nicol Vaizman
Nicol Vaizman is a Master’s student in Medical Genetics at UBC, based in the Brunham Lab at the HLI. Her research explores how genetic testing can identify and manage inherited lipid disorders, aiming to prevent cardiovascular disease and translating genetic data into practical tools for clinicians and patients.

Doctors often use a routine lipid panel – a blood test that measures levels of fat in the blood – to assess cardiovascular risk. Cardiovascular disease remains the leading cause of death worldwide. Among the many numbers a lipid panel reports, one is often missing despite its strong ability to predict heart disease. That number is Lipoprotein(a) or Lp(a). Though elevated Lp(a) levels are found in around 1.6 billion people globally, it is almost never measured. 

A recent review paper published in the European Journal of Preventive Cardiology, led by physician-scientists at the Centre for Heart Lung Innovation (HLI) and McGill University, argues that it is time to change how and when we test for this overlooked risk factor. 

The review, written by Drs. Iulia Iatan and Gordon Francis, with co-authors Drs. Liam Brunham and John Mancini, presents a comprehensive case for testing Lp(a). It draws on clinical guidelines, epidemiologic and genetic data, and public health principles.

As Dr. Gordon Francis notes, “It is now recommended that Lp(a) be measured at the same time as the first cholesterol profile.”

How Lp(a) is unique and why it matters

Lp(a) is not your typical cholesterol biomarker. Unlike low-density lipoprotein (LDL) cholesterol – the “bad” cholesterol that raises heart disease risk and can change with diet or lifestyle changes – Lp(a) levels are genetically determined and remain stable throughout life.

Years of large-scale and genetic studies have shown that Lp(a) is an independent, causal risk factor for atherosclerotic cardiovascular disease and aortic stenosis. In other words, Lp(a) is associated with the development of both blocked arteries and narrowing of the heart valves. The higher someone’s Lp(a) is, the greater their risk is. Importantly, this risk is present even in individuals with low LDL cholesterol levels.

“The risk of atherosclerotic cardiovascular disease with markedly elevated Lp(a) is equal to that of untreated familial hypercholesterolemia.” – Dr. Gordon Francis

The authors cite a major study of 5.5 million U.S patients, where less than 1% had their Lp(a) levels measured. Yet, it is estimated that 1 in 5 people worldwide have elevated levels (Lp(a) > 125 nmol/L), making it as common as high blood pressure or smoking in some populations.

The evidence is clear, but underused

When evaluating Lp(a) against classical and modern population-level screening principles, the authors’ conclusion was clear: Lp(a) screening checks nearly every box. It is common, easy to measure with a reliable and simple blood test, provides actionable information to guide patient care, and is cost-effective.

In British Columbia, a one-time Lp(a) test costs just $29.61. As the authors note, “the value of knowing the result of the test is likely to be higher than the cost of the test.” That value includes helping doctors better predict who is most at risk so that they can intervene earlier and potentially prevent cardiovascular events and reduce associated healthcare costs.

While there is not yet an approved treatment that directly lowers Lp(a), several therapies are in late-stage clinical trials and expected to report outcomes within the next year. Still, the authors emphasize that Lp(a) testing can already be useful in informing care. Knowing a patient’s Lp(a) level can help clinicians decide whether to lower other modifiable risk factors more intensively, such as lowering LDL cholesterol levels or prioritizing imaging.

Test results can also prompt screening of family members, especially when there is history of premature cardiovascular disease or inherited high cholesterol (familial hypercholesterolemia).

According to Dr. Iulia Iatan, “When we identify a patient with elevated Lp(a), it’s not just about that individual – it’s an opportunity to screen family members and intervene earlier.”

As Dr. Francis notes, “When elevated Lp(a) is found, it is recommended to review the family history for premature cardiovascular events, try to reduce all other risk factors like smoking or elevated blood pressure, possibly perform a blood vessel imaging study like a carotid ultrasound or coronary calcium score, and consider initiating statin therapy to mitigate the risk of the high Lp(a).”

Global guidelines already recommend Lp(a) screening

International guidelines are beginning to reflect the growing consensus on the importance of Lp(a). Canadian and European lipid guidelines, as well as the American National Lipid Association, now recommend one-time Lp(a) testing for all adults, preferably when they get their first lipid panel.

Yet, as the paper highlights, “this recommendation has not been incorporated into a formalized screening programme in any health jurisdiction to our knowledge.” The authors suggest that Lp(a) testing could serve as a catalyst to reevaluate how lipids are screened at the population level.

Awareness isn’t enough

The authors conclude with a clear call to action: “The time has come to qualify Lp(a) as a routine screening test for cardiovascular risk assessment based on these cornerstone criteria.”

This paper reflects the ongoing leadership of physician-scientists at HLI, who continue to shape the future of proactive preventive medicine. Their efforts are helping change how inherited cardiovascular risks are detected, managed, and ultimately prevented in routine care.

Take a look at the full open-access article here:

Iulia Iatan, Marlys L Koschinsky, Logan Trenaman, Wei Zhang, George Thanassoulis, Liam R Brunham, G B John Mancini, Gordon A Francis, Rationale for the routine screening of Lipoprotein(a) in cardiovascular risk assessment, European Journal of Preventive Cardiology, 2025;, zwaf342, https://doi.org/10.1093/eurjpc/zwaf342

By Jinelle Panton
Jinelle Panton is a PhD student in the Camp lab.