Centre for Heart Lung Innovation
St. Paul's Hospital
Room 166 - 1081 Burrard Street
Vancouver, B.C. V6Z 1Y6
Dr. Luo’s main research interests lie in the study of understanding the mechanisms leading to the pathogenesis of viral myocarditis. The focus of Dr. Luo’s research program is to define the pathogenetic determinants of virus-host interactions in enterovirus-induced heart disease. The ongoing research projects include: 1) Protein degradation pathways, including the ubiquitin/proteasome pathway and the autophagy, in virus-induced myocarditis and dilated cardiomyopathy; and 2) The molecular mechanisms of impaired cardiac function in viral myocarditis. Dr. Luo has published 82 refereed papers and 7 book chapters. Most of these publications have been appeared in leading journals, including Circulation, Journal of Virology, Cell Death and Differentiation, Cell Host and Microbe, Diabetes, Journal of Biological Chemistry, American Journal of Pathology, and Circulation Research.
Dr. Luo was a Canadian Institutes of Health Research/St. Paul’s Hospital Foundation New Investigator and a Michael Smith Foundation for Health Research Scholar. Dr. Luo was awarded a Canada Foundation for Innovation New Opportunities grant in acquiring cutting-edge infrastructure. Her work on the roles of protein degradation system and host signaling in virus-mediated myocarditis were supported by the Canadian Institutes of Health Research, the Heart & Stroke Foundation of Canada, and the Hospital for Sick Kids Foundation.
Education and Training
- West China University of Medical Sciences MS, Hemodynamics, 1989
- Chongqing Medical University MD, Medicine, 1986
- University of Washington Postdoc, Pathology, 1997-2000
Area of Interest
Antivirals, Cardiomyopathy, Cell Signaling, Heart Failure, Protein Quality Control, Viral Infections