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ServicesMolecular Phenotyping

Comprehensive characterization of biological samples

The Molecular Phenotyping Core Laboratory (MPCL) at the Centre for Heart Lung Innovation (HLI) is a fee-for-service, multi-user laboratory. The MPCL provides research tools and technical support to researchers and clinicians both within the HLI and Providence Healthcare, and external groups from the Lower Mainland research community and beyond.

Evolving from the fusion of the Flow Cytometry and Genotyping laboratories, and expanded by funding from the Canada Foundation for Innovation, the MPCL provides a unique environment for the complete characterization of biological samples. Members of the MPCL are involved in studies of cell phenotyping, protein profiling, genotyping and gene expression in order to further our understanding of the pathogenesis of cardiovascular, respiratory and systemic inflammatory diseases including transplant rejection, asthma and COPD. The MPCL consists of five integrated areas of focus: flow cytometry, genotyping, RNA analysis, multiplex protein analyses and laser capture microdissection. These core technologies combined with our specialized staff create an enhanced environment of synergy. This ultimately leads to a greater understanding of cardiovascular and pulmonary diseases that can be effectively translated into improved patient care.

Beth Whalen

Core Manager

Ms. Whalen holds a BSc from Memorial University of Newfoundland, and has been working at HLI for almost 30 years.

Basak Sahin

MSc, Technician

Ms. Sahin holds a BSc in Molecular Biology and Genetics from METU and a MSc in Biomedical Sciences (U. Alberta).