|Title||A rare cardiac neoplasm: case report of cardiac epithelioid angiosarcoma.|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Matzke, LAnne Marie, Knowling, MA, Grant, D, Cupples, JB, Leipsic, J, Ignaszewski, A, Allard, MF|
|Date Published||2011 Sep-Oct|
|Keywords||Aorta, Abdominal, Atrial Fibrillation, Combined Modality Therapy, Echocardiography, Transesophageal, Epithelioid Cells, Fatal Outcome, Heart Atria, Heart Neoplasms, Hemangiosarcoma, Humans, Male, Middle Aged, Tumor Markers, Biological|
Primary cardiac angiosarcoma is a rare neoplasm and the epithelioid variant is exceedingly rare. We report a case of an epithelioid angiosarcoma that involved the right atrium and aorta of a 47-year-old male. The patient presented with atrial fibrillation and presyncopal spells. Following clinical evaluation, including computed tomography scan and trans-esophageal echocardiography, the neoplasm was surgically removed. It was a poorly differentiated malignant neoplasm composed of medium-sized epithelioid cells with a moderate amount of amphophilic cytoplasm. Immunohistochemical staining, including positive staining for CK22, AE1/AE3, melan-A, vimentin, and CD31, indicated the neoplasm was best categorized as an epithelioid angiosarcoma.
|Alternate Journal||Cardiovasc. Pathol.|