Tillie-Louise Hackett, PhD

Associate Professor
Department of Anesthesiology, Pharmacology & Therapeutics

Centre for Heart Lung Innovation

Room 166, 1081 Burrard Street

Vancouver, BC V6Z 1Y6

Phone Number: 
(604) 682-2344 x62563
Fax Number: 
(604) 806-8351
Email Address: 

Dr. Hackett received her BSc. in Biochemistry and Pharmacology and her Ph.D. in Cellular and Biological Sciences from the University of Southampton, in the UK under the mentorship of Dr. J.A. Warner and Prof. S.T. Holgate. In 2006, Dr Hackett joined the James Hogg Research Centre at the University of British Columbia, Canada funded by a Canadian Institutes for Health, Canadian Lung Association and Michael Smith Foundation for Health Research post doctoral fellowships with Drs D.A. Knight and T. Bai. Dr. Hackett then undertook additional postdoctoral training at the University Medical Centre Groningen fundied by the European Respiratory Society, with Prof. D.S. Postma and Dr. H.I. Heijink. Dr. Hackett began her academic appointment at UBC as an Assistant Professor in 2013. She receives funding from the Canadian Institutes for Health Research (CIHR), Canadian Lung Association, Parker B. Francis Foundation, Providence Health Care Research Institute and UBC Faculty of Medicine. In 2018, Dr. Hackett was awarded a UBC Faculty of Medicine Distinguished Achievement Award for Excellence in Basic Science Research and appointed as an Inaugural Fellow of the American Thoracic Society.


Teaching and Training

In addition to undergraduate and graduate teaching, Dr. Hackett has supervised over 40 outstanding and accomplished trainees. Together, they have won over 63 awards totaling $680,000 in competitive research funding since 2013. This includes prestigious fellowships from CIHR, Michael Smith Foundation for Health Research, and the Canadian Lung Association, tuition awards from UBC, as well as travel and presentation awards at over 15 local, national, and international conferences.


Education and Training

  • BSc, Biochemistry and Pharmacology, University of Southampton (2002)
  • PhD, Cellular and Biological Sciences, University of Southampton (2006)

Area of Interest

Dr. Hackett's research program is focused on understanding the disruption of normal repair processes within the epithelial-mesenchymal trophic unit (EMTU) of the lung and how this propagates inflammation and tissue remodeling in patients with obstructive lung disease. Her laboratory uses an innovative and targeted approach to isolate cells from donor lungs guided by Computed Tomography imaging. This resource, The Human Lung Cell Repository, aims to provide highly characterized cells representative of a variety of lung disease states and healthy individuals for use in clinical bio-assays of disease. The goal of this research program is to further understand the airway microenvironment to determine therapeutic targets to prevent the initiation and perpetuation of pathological processes which contribute to obstructive airway diseases like asthma and chronic obstructive pulmonary disease.

Selected Publications