Biblio

Found 12 results
Filters: Author is Brunham, Liam R  [Clear All Filters]
2015
L. R. Brunham, Kang, M. H., Van Karnebeek, C., Sadananda, S. N., Collins, J. A., Zhang, L. - H., Sayson, B., Miao, F., Stockler, S., Frohlich, J., Cassiman, D., Rabkin, S. W., and Hayden, M. R., “Clinical, Biochemical, and Molecular Characterization of Novel Mutations in ABCA1 in Families with Tangier Disease.”, JIMD Rep, vol. 18, pp. 51-62, 2015.
L. R. Brunham and Hayden, M. R., “Human genetics of HDL: Insight into particle metabolism and function.”, Prog Lipid Res, vol. 58, pp. 14-25, 2015.
2013
L. R. Brunham and Hayden, M. R., “Hunting human disease genes: lessons from the past, challenges for the future.”, Hum Genet, vol. 132, no. 6, pp. 603-17, 2013.
2012
L. R. Brunham and Hayden, M. R., “Whole-genome sequencing: the new standard of care?”, Science, vol. 336, no. 6085, pp. 1112-3, 2012.
2010
M. Vergeer, Brunham, L. R., Koetsveld, J., Kruit, J. K., C Verchere, B., Kastelein, J. J. P., Hayden, M. R., and Stroes, E. S. G., “Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction.”, Diabetes Care, vol. 33, no. 4, pp. 869-74, 2010.
2009
L. R. Brunham, Singaraja, R. R., Duong, M. N., Timmins, J. M., Fievet, C., Bissada, N., Kang, M. H., Samra, A., Fruchart, J. - C., McManus, B., Staels, B., Parks, J. S., and Hayden, M. R., “Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.”, Arterioscler Thromb Vasc Biol, vol. 29, no. 4, pp. 548-54, 2009.
2008
L. R. Brunham, Kruit, J. K., C Verchere, B., and Hayden, M. R., “Cholesterol in islet dysfunction and type 2 diabetes.”, J Clin Invest, vol. 118, no. 2, pp. 403-8, 2008.
2007
L. R. Brunham, Kruit, J. K., Pape, T. D., Timmins, J. M., Reuwer, A. Q., Vasanji, Z., Marsh, B. J., Rodrigues, B., Johnson, J. D., Parks, J. S., C Verchere, B., and Hayden, M. R., “Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.”, Nat Med, vol. 13, no. 3, pp. 340-7, 2007.
2006
L. R. Brunham, Kruit, J. K., Iqbal, J., Fievet, C., Timmins, J. M., Pape, T. D., Coburn, B. A., Bissada, N., Staels, B., Groen, A. K., M Hussain, M., Parks, J. S., Kuipers, F., and Hayden, M. R., “Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.”, J Clin Invest, vol. 116, no. 4, pp. 1052-62, 2006.
L. R. Brunham, Kruit, J. K., Pape, T. D., Parks, J. S., Kuipers, F., and Hayden, M. R., “Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.”, Circ Res, vol. 99, no. 7, pp. 672-4, 2006.
L. R. Brunham, Singaraja, R. R., and Hayden, M. R., “Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis.”, Annu Rev Nutr, vol. 26, pp. 105-29, 2006.
2005
L. R. Brunham, Singaraja, R. R., Pape, T. D., Kejariwal, A., Thomas, P. D., and Hayden, M. R., “Accurate prediction of the functional significance of single nucleotide polymorphisms and mutations in the ABCA1 gene.”, PLoS Genet, vol. 1, no. 6, p. e83, 2005.