Found 562 results
A. Tam, Hughes, M., McNagny, K. M., Obeidat, M., Hackett, T. L., Leung, J. M., Shaipanich, T., Dorscheid, D., Singhera, G. K., Yang, C. W. T., Paré, P. D., Hogg, J. C., Nickle, D., and Sin, D., Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease, Scientific Reports, vol. 9, no. 1, 2019.
S. Shafaattalab, Lin, E., Christidi, E., Huang, H., Nartiss, Y., Garcia, A., Lee, J., Protze, S., Keller, G., Brunham, L. R., Tibbits, G. F., and Laksman, Z. W., Ibrutinib displays atrial-specific toxicity in human stem cell-derived cardiomyocytes, Stem Cell Reports, vol. 12, no. 5, pp. 996-1006, 2019.
B. C. Lo, Shin, S. B., CanalsHernaez, D., Refaeli, I., Yu, H. B., Goebeler, V., Cait, A., Mohn, W. W., Vallance, B. A., and McNagny, K. M., IL-22 preserves gut epithelial integrity and promotes disease remission during chronic Salmonella infection, Journal of Immunology, vol. 202, no. 3, pp. 956-965, 2019.
J. Cait, Hughes, M., Zeglinski, M. R., Chan, A. W., Osterhof, S., Scott, R. W., CanalsHernaez, D., Cait, A., Vogl, A. W., Bernatchez, P. N., Underhill, T. M., Granville, D. J., Murphy, T. H., Roskelley, C. D., and McNagny, K. M., Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation, Proceedings of the National Academy of Sciences, 2019.
F. S. LeitaoFilho, Alotaibi, N. M., Ngan, D., Tam, S., Yang, J., Hollander, Z., Chen, V., Fitzgerald, J. M., Nislow, C., Leung, J. M., Man, S. F. P., and Sin, D., Sputum microbiome is associated with 1-year mortality after chronic obstructive pulmonary disease hospitalizations, American Journal of Respiratory and Critical Care Medicine, vol. 199, no. 10, pp. 1205-1213, 2019.
D. Sin, What's in the CART? A decision rule to predict short-term mortality during COPD exacerbations, Respirology, 2019.
Y. Asai, Eslami, A., van Ginkel, C., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I., Martino, D., Ferreira, M. A., Allen, K., Mazer, B., de Groot, H., de Jong, N. W., van Wijk, R. G., Dubois, A. E., Grosche, S., Ruschendorf, F., Kalb, B., Beyer, K., Nothen, M. M., Young-Ae, L., Chin, R., Cheuk, S., Hoffman, J., Jorgenson, E., Witte, J. S., Melles, R. B., Hon, X., Wang, X., Hui, J., Musk, A. W., Hunter, M., James, A. L., Koppelmann, G. H., Sandford, A. J., Clarke, A. E., and Daley, D., Canadian genome-wide association study and meta analysis confirm HLA as a risk factor for peanut allergy independent of asthma, Journal of Allergy and Clinical Immunology, 2018.
S. Xu, Tsai, A., Sze, M. A., Vucic, E. A., Shaipanich, T., Harris, M., Guillemi, S., Yang, J., Sinha, S., Nislow, C., Montaner, J., Lam, W., Lam, S., Sin, D. D., Man, S. F. P., and Leung, J. M., Decreased microbiome diversity in the HIV small airway epithelium, Respiratory Research, vol. 19, no. 1, 2018.
M. Obeidat, Zhou, G., Li, X., Hansel, N. N., Rafaels, N., Mathias, R., Ruczinski, I., Beaty, T. H., Barnes, K. C., Paré, P. D., and Sin, D. D., The genetics of smoking in individuals with chronic obstructive pulmonary disease, Respiratory Research, vol. 19, no. 1, 2018.
F. Demenais, Margaritte-Jeanin, P., Barnes, K. C., Cookson, W. O. C., Altmueller, J., Ang, W., Barr, R. G., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E., Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., A Alves, C., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., del-Rio-Navarro, B., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Australian-Asthma-Genetics-Consortium, collaborators, Freidin, M. B., Gajdos, G., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P., Gudjartsson, D. F., Haahtela, T., ,, Heederik, D., Heinrich, J., Heliövaara, M., Henderon, J., Himes, B. E., and et, al, Multi-ancestry genome-wide association study identifies new asthma susceptibility loci that co-localize with immune cell enhancer histone marks, Nature Genetics, vol. 50, no. 1, pp. 42-53, 2018.
M. Obeidat, Dvorkin-Gheva, A., Li, X., Bossé, Y., Brandsma, C. A., Nickle, D. C., Hansbro, P. M., Faner, R., Agusti, A., Paré, P. D., Stampfli, M. R., and Sin, D., The overlap of lung tissue transcriptome of smoke exposed mice with human smoking and COPD, Scientific Reports, vol. 8, no. 1, 2018.
S. Barichello, Roberts, J. D., Backx, P., Boyle, P. M., and Laksman, Z. W., Personalizing therapy for atrial fibrillation: the role of stem cell and in silico disease models, Cardiovascular Research, vol. 114, no. 7, pp. 931-943, 2018.
P. G. Woodruff, van den Berge, M., Boucher, R. C., Brightling, C., Burchard, E. G., Chirstenson, S. A., Han, M. K., Holtzman, M. J., Kraft, M., Lynch, D. A., Martinez, F. D., Reddel, H. K., Sin, D., Washko, G. R., Wenzel, S. E., Punturieri, A., Freemer, M. M., and Wise, R. A., American Thoracic Society/National Heart, Lung, and Blood Institute Asthma–Chronic Obstructive Pulmonary Disease Overlap Workshop Report, vol. 196, no. 3, pp. 375-381, 2017.
L. Mostaço-Guidolin, Hajimohammadi, S., Vasilescu, D. M., and Hackett, T. L., Application of Euclidean distance mapping for assessment of basement membrane thickness distribution in asthma, Journal of Applied Physiology (1985), vol. 123, no. 2, pp. 473-481, 2017.
S. L. Chan, Chua, A. P. G., Aminkeng, F., Chee, C. B. E., Jin, S., Loh, M., Gan, S. H., Wang, Y. T., and Brunham, L. R., Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients, PLoS One, vol. 12, no. 10, p. e0186200, 2017.
B. Rush, Wishar, K., Celi, L. A., Walley, K. R., Russell, J. A., McDermid, R. C., and Boyd, J. H., Association of Household Income Level and In-Hospital Mortality in Patients With Sepsis: A Nationwide Retrospective Cohort Analysis, Journal of Intensive Care Medicine, vol. 1, no. 6, 2017.
J. M. Leung and Sin, D., Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets, BMJ, vol. 348, 2017.
Z. Hollander, DeMarco, M. L., Sadatsafavi, M., McManus, B. M., Ng, R. T., and Sin, D., Biomarker development in COPD: moving from P values to products to impact patient care, Chest, vol. 151, no. 2, pp. 455-467, 2017.
R. Parkash, Thibault, B., Philippon, F., Mangat, I., Coutu, B., Bennett, M., Crystal, E., Healey, J., Verma, A., Sandhu, R., Cameron, D., Ayala-Paredes, F., Sterns, L., Essebag, V., Sturmer, M., Nery, P., Wells, G., and Krahn, A., Canadian Registry of Implantable Electronic Device Outcomes: Longer Term Follow up of the Riata Lead Under Advisory, Heart Rhythm, 2017.
H. Deng, Fung, G., Qiu, Y., Wang, C., Zhang, J., Jin, Z. G., and Luo, H., Cleavage of Grb2-Associated Binding Protein 2 by Viral Proteinase 2A during Coxsackievirus Infection, Frontiers in Cellular and Infection Microbiology, vol. 7, 2017.
Y. Qiu, Ye, X., Zhang, H. M., Hanson, P., Zhao, G., Tong, L., Xie, R., and Yang, D., Cleavage of osmosensitive transcriptional factor NFAT5 by Coxsackieviral protease 2A promotes viral replication, PLOS Pathogens, vol. 13, no. 12, p. e1006744, 2017.
L. R. Brunham, Cermakova, L., Lee, T., Priecelova, I., Alloul, K., de Chantal, M., Francis, G. A., and Frohlich, J., Contemporary Trends in the Management and Outcomes of Patients With Familial Hypercholesterolemia in Canada: A Prospective Observational Study, Canadian Journal of Cardiology, vol. 33, no. 3, pp. 385-392, 2017.
J. C. Hogg, Paré, P. D., and Hackett, T. L., The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease, Physiological Reviews, vol. 97, no. 2, pp. 529-552, 2017.
J. M. Leung, Chen, V., Hollander, Z., Dai, D., Tebbutt, S. J., Aaron, S. D., Vandemheen, K., Rennard, S. I., Fitzgerald, J. M., Woodruff, P. G., Lazarus, S. C., Connett, J. E., Coxson, H. O., Miller, B., Borcher, C., McManus, B. M., Ng, R. T., and Sin, D., COPD exacerbation biomarkers validated using multiple reaction monitoring mass spectrometry, PLoS One, vol. 11, no. 8, p. e0161129, 2017.
A. Sharma, Yuen, D., Huet, O., Pickering, R., Stefanovic, N., Bernatchez, P., and de Haan, J. B., Corrigendum to "Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium", Vascular Pharmacology, vol. 99, 2017.