Found 570 results
L. Mostaço-Guidolin, Osei, E. T., Ullah, J., Hajimohammadi, S., Fouadi, M., Li, X., Li, V., Shaheen, F., Yang, C. X., Chu, F., Cole, D. J., Brandsma, C. A., Heijink, I. H., Maksym, G. N., Walker, D., and Hackett, T. L., Defective Fibrillar Collagen Organization by Fibroblasts Contributes to Airway Remodeling in Asthma, American Journal of Respiratory Critical Care Medicine, vol. 200, no. 4, pp. 431-443, 2019.
A. Tam, Hughes, M., McNagny, K. M., Obeidat, M., Hackett, T. L., Leung, J. M., Shaipanich, T., Dorscheid, D., Singhera, G. K., Yang, C. W. T., Paré, P. D., Hogg, J. C., Nickle, D., and Sin, D., Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease, Scientific Reports, vol. 9, no. 1, 2019.
S. Shafaattalab, Lin, E., Christidi, E., Huang, H., Nartiss, Y., Garcia, A., Lee, J., Protze, S., Keller, G., Brunham, L. R., Tibbits, G. F., and Laksman, Z. W., Ibrutinib displays atrial-specific toxicity in human stem cell-derived cardiomyocytes, Stem Cell Reports, vol. 12, no. 5, pp. 996-1006, 2019.
B. C. Lo, Shin, S. B., CanalsHernaez, D., Refaeli, I., Yu, H. B., Goebeler, V., Cait, A., Mohn, W. W., Vallance, B. A., and McNagny, K. M., IL-22 preserves gut epithelial integrity and promotes disease remission during chronic Salmonella infection, Journal of Immunology, vol. 202, no. 3, pp. 956-965, 2019.
D. M. Vasilescu, Martinez, F. J., Marchetti, N., Galbán, C. J., Hatt, C., Meldrum, C. A., Dass, C., Tanabe, N., Reddy, R. M., Lagstein, A., Ross, B. D., Labaki, W. W., Murray, S., Xia, M., Curtis, J. L., Hackett, T. L., Kazerooni, E. A., Criner, G. J., Hogg, J. C., and Han, M. K., Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease, American Journal of Respiratory Critical Care Medicine, vol. 200, no. 5, pp. 575-581, 2019.
J. Cait, Hughes, M., Zeglinski, M. R., Chan, A. W., Osterhof, S., Scott, R. W., CanalsHernaez, D., Cait, A., Vogl, A. W., Bernatchez, P. N., Underhill, T. M., Granville, D. J., Murphy, T. H., Roskelley, C. D., and McNagny, K. M., Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation, Proceedings of the National Academy of Sciences, 2019.
F. S. LeitaoFilho, Alotaibi, N. M., Ngan, D., Tam, S., Yang, J., Hollander, Z., Chen, V., Fitzgerald, J. M., Nislow, C., Leung, J. M., Man, S. F. P., and Sin, D., Sputum microbiome is associated with 1-year mortality after chronic obstructive pulmonary disease hospitalizations, American Journal of Respiratory and Critical Care Medicine, vol. 199, no. 10, pp. 1205-1213, 2019.
D. Sin, What's in the CART? A decision rule to predict short-term mortality during COPD exacerbations, Respirology, 2019.
R. L. Clifford, Fishbane, N., Patel, J., MacIsaac, J. L., McEwen, L. M., Fisher, A. J., Brandsma, C. A., Nair, P., Kobor, M. S., Knox, A. J., and Hackett, T. L., Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD, Clinical Epigenetics, vol. 10, no. 32, 2018.
Y. Asai, Eslami, A., van Ginkel, C., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I., Martino, D., Ferreira, M. A., Allen, K., Mazer, B., de Groot, H., de Jong, N. W., van Wijk, R. G., Dubois, A. E., Grosche, S., Ruschendorf, F., Kalb, B., Beyer, K., Nothen, M. M., Young-Ae, L., Chin, R., Cheuk, S., Hoffman, J., Jorgenson, E., Witte, J. S., Melles, R. B., Hon, X., Wang, X., Hui, J., Musk, A. W., Hunter, M., James, A. L., Koppelmann, G. H., Sandford, A. J., Clarke, A. E., and Daley, D., Canadian genome-wide association study and meta analysis confirm HLA as a risk factor for peanut allergy independent of asthma, Journal of Allergy and Clinical Immunology, 2018.
S. Post, Heijink, I. H., Hesse, L., Koo, H. K., Shaheen, F., Fouadi, M., Kuchibhotla, V. N. S., Lambrecht, B. N., Van Oosterhout, A. J. M., Nawijn, M. C., and Hackett, T. L., Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology, Scientific Reports, vol. 8, no. 1, 2018.
S. Xu, Tsai, A., Sze, M. A., Vucic, E. A., Shaipanich, T., Harris, M., Guillemi, S., Yang, J., Sinha, S., Nislow, C., Montaner, J., Lam, W., Lam, S., Sin, D. D., Man, S. F. P., and Leung, J. M., Decreased microbiome diversity in the HIV small airway epithelium, Respiratory Research, vol. 19, no. 1, 2018.
S. Booth and Hackett, T. L., Gene expression signature of the ageing lung: breathing new life into COPD, Thorax, vol. 73, pp. 605-606, 2018.
M. Obeidat, Zhou, G., Li, X., Hansel, N. N., Rafaels, N., Mathias, R., Ruczinski, I., Beaty, T. H., Barnes, K. C., Paré, P. D., and Sin, D. D., The genetics of smoking in individuals with chronic obstructive pulmonary disease, Respiratory Research, vol. 19, no. 1, 2018.
F. Demenais, Margaritte-Jeanin, P., Barnes, K. C., Cookson, W. O. C., Altmueller, J., Ang, W., Barr, R. G., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E., Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., A Alves, C., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., del-Rio-Navarro, B., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Australian-Asthma-Genetics-Consortium, collaborators, Freidin, M. B., Gajdos, G., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P., Gudjartsson, D. F., Haahtela, T., ,, Heederik, D., Heinrich, J., Heliövaara, M., Henderon, J., Himes, B. E., and et, al, Multi-ancestry genome-wide association study identifies new asthma susceptibility loci that co-localize with immune cell enhancer histone marks, Nature Genetics, vol. 50, no. 1, pp. 42-53, 2018.
M. Obeidat, Dvorkin-Gheva, A., Li, X., Bossé, Y., Brandsma, C. A., Nickle, D. C., Hansbro, P. M., Faner, R., Agusti, A., Paré, P. D., Stampfli, M. R., and Sin, D., The overlap of lung tissue transcriptome of smoke exposed mice with human smoking and COPD, Scientific Reports, vol. 8, no. 1, 2018.
S. Barichello, Roberts, J. D., Backx, P., Boyle, P. M., and Laksman, Z. W., Personalizing therapy for atrial fibrillation: the role of stem cell and in silico disease models, Cardiovascular Research, vol. 114, no. 7, pp. 931-943, 2018.
H. Y. Koo, Vasilescu, D. M., Booth, S., Hsieh, A., Katsamenis, O., Fishbane, N., Elliott, W. M., Kirby, M., Lackie, P., Sinclair, I., Warner, J. A., Cooper, J. D., Coxson, H. O., Paré, P. D., Hogg, J. C., and Hackett, T. L., Small Airways Disease in Mild to Moderate Chronic Obstructive Pulmonary Disease: a cross sectional study, The Lancet Respiratory Medicine, vol. 6, no. 8, pp. 591-602, 2018.
P. G. Woodruff, van den Berge, M., Boucher, R. C., Brightling, C., Burchard, E. G., Chirstenson, S. A., Han, M. K., Holtzman, M. J., Kraft, M., Lynch, D. A., Martinez, F. D., Reddel, H. K., Sin, D., Washko, G. R., Wenzel, S. E., Punturieri, A., Freemer, M. M., and Wise, R. A., American Thoracic Society/National Heart, Lung, and Blood Institute Asthma–Chronic Obstructive Pulmonary Disease Overlap Workshop Report, vol. 196, no. 3, pp. 375-381, 2017.
L. Mostaço-Guidolin, Hajimohammadi, S., Vasilescu, D. M., and Hackett, T. L., Application of Euclidean distance mapping for assessment of basement membrane thickness distribution in asthma, Journal of Applied Physiology (1985), vol. 123, no. 2, pp. 473-481, 2017.
S. L. Chan, Chua, A. P. G., Aminkeng, F., Chee, C. B. E., Jin, S., Loh, M., Gan, S. H., Wang, Y. T., and Brunham, L. R., Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients, PLoS One, vol. 12, no. 10, p. e0186200, 2017.
B. Rush, Wishar, K., Celi, L. A., Walley, K. R., Russell, J. A., McDermid, R. C., and Boyd, J. H., Association of Household Income Level and In-Hospital Mortality in Patients With Sepsis: A Nationwide Retrospective Cohort Analysis, Journal of Intensive Care Medicine, vol. 1, no. 6, 2017.
J. M. Leung and Sin, D., Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets, BMJ, vol. 348, 2017.
Z. Hollander, DeMarco, M. L., Sadatsafavi, M., McManus, B. M., Ng, R. T., and Sin, D., Biomarker development in COPD: moving from P values to products to impact patient care, Chest, vol. 151, no. 2, pp. 455-467, 2017.
R. Parkash, Thibault, B., Philippon, F., Mangat, I., Coutu, B., Bennett, M., Crystal, E., Healey, J., Verma, A., Sandhu, R., Cameron, D., Ayala-Paredes, F., Sterns, L., Essebag, V., Sturmer, M., Nery, P., Wells, G., and Krahn, A., Canadian Registry of Implantable Electronic Device Outcomes: Longer Term Follow up of the Riata Lead Under Advisory, Heart Rhythm, 2017.